EU drug authority is examining approval of corona drug Ronapreve

EU Medicines Agency examines approval of Corona drug

The European Medicines Agency Ema is reviewing the approval of another corona drug. The Swiss pharmaceutical company Roche has submitted an application for approval of its antibody therapy Ronapreve , announced the Ema on Monday in Amsterdam.

The drug, which consists of two active ingredients (casirivimab and imdevimab) and was co-produced by the US manufacturer Regeneron Pharmaceuticals, is intended to People from 12 years are treated, the are infected with the coronavirus and are at high risk of severe disease. In addition, according to the manufacturer, the agent can also be used in people who are at an acute risk of infection , for example because they live in a household with an infected person.

Just recently the World Health Organization (WHO) had the cocktail of casirivimab and imdevimab for the prevention of severe Covid – 19 – Disease recommended in infected risk patients . In Germany, this antibody combination is already used in special cases for corona patients.

The Ema experts now evaluate all the data presented and weigh the advantages and disadvantages of the preparation against each other. With one result is expected in two months. The experts had already checked the manufacturer’s research results before the manufacturer submitted an official application. This shortens the approval process.

So far, only the drug Remdesivir has been approved as a special corona drug in the EU. A total of five preparations are currently being approved. (dpa)

Bei den Corona-Protesten in der italienischen Hauptstadt kam es zu Zusammenstößen zwischen Demonstranten und der Polizei.
During the Corona protests in the Italian capital, there were clashes between demonstrators and the police. Image: Mauro Scrobogna / LaPresse / AP / dpa

Italy’s judiciary determined after corona riots

after the riots at corona demonstrations in Rome last Weekend investigates the prosecutor. The judiciary has opened two proceedings against several persons , which, among other things, in the attack on the headquarters of the CGIL should have been there on Saturday, the Ansa news agency reported on Monday.

Prime Minister Mario Draghi visited CGIL General Secretary Maurizio Landini there on Monday afternoon. Supporters of the right-wing and neo-fascist Forza Nuova (Neue Kraft) party attacked the seat on Saturday on the sidelines of demonstrations against the government’s corona measures. The flying visit of the head of government was an “important message” for democracy and against “a return to the past, which must be prevented,” said Landini. At the roughly thirty-minute meeting, Landini said after the meeting of journalists, the two had also talked about the demand for a dissolution of fascist parties such as the Forza Nuova . Such a step has been discussed by politicians since Saturday.

The social democratic party PD introduced a motion to the Senate on Monday calling on the government to do the to tackle the break-up of Forza Nuova and other fascist parties . Other senators made similar proposals. Overall, according to media reports around 17 People hurt . The rioters also targeted a hospital on Saturday evening .

The background to the demonstrations is that from the 15. October, a corona vaccination certificate, a negative test for the virus or the certified recovery from the disease should also be mandatory in the world of work. In Italy these certificates are called “Green Passports”. (dpa)

Study: Antibody cocktail from Astrazeneca effective against corona

In the fight against corona, Astrazeneca achieved positive results in a study with an experimental antibody combination. In the study, the antibody combination reduced the number of seriously ill and dead people among corona infected people , as the British pharmaceutical company announced.

In patients who have had symptoms for seven days or less and do not require hospital treatment, the risk of a severe Covid – 19 – to develop or die of the disease in order to 50 percent reduced . This results in the late phase of the study with the drug called AZD 307.

“An early intervention with our antibody can significantly reduce the progression of the disease and offers protection for over six months,” explains Astrazeneca manager Mene Pangalos. The group has already applied for an emergency permit from the US authorities for the approval of the antibody cocktail as a preventive agent. (Reuters)

No uniform test requirement for employees with customer contact

The federal government and the federal states could not agree on a uniform procedure for the exemption of a corona test obligation for employees in companies with public traffic . The Conference of Health Ministers decided on Monday in its switching conference that Paragraph 28 in the Infection Protection Act as the legal basis for this may be. “On this legal basis, a test submission obligation for employees with direct customer contact can be issued by state law ,” says the unanimous decision of the German press Agency is available.

In the original draft it was said: “The federal states agree that this is now regulated in many federal states 3G proof of obligation as a prerequisite for access to companies, facilities or other offers with direct customer contact should apply not only to customers, visitors or other external persons, but also to employees. ” (dpa)

WHO recommends booster vaccination for immunocompromised patients

The World Health Organization (WHO) has recommended a Corona booster vaccination for immunocompromised patients. People with “moderately to severely damaged” immune systems should be offered a booster vaccination , the WHO said on Monday in Geneva. This applies to all vaccines recommended by the WHO.

People with a weakened immune system could only react to the standard vaccination to a limited extent. Therefore they are subject to a “ high risk of severe Covid – 19-Illness “stated the WHO Expert Group on Immunizations (Sage). However, the WHO did not speak out in favor of a so-called booster vaccination for all population groups. (AFP)

Bayerns Ressortchef Klaus Holetschek (CSU)
Bavaria’s head of department Klaus Holetschek (CSU) Image : Imago Images / Sven Simon

Holetschek calls for RKI report on corrected vaccination numbers

In view of corrected vaccination numbers, Bavaria’s head of department calls for Klaus Holetschek (CSU) in the next line of health ministers a report from the Robert Koch Institute (RKI). “ We need clarity and truth in the question of the data ,” said Holetschek on Monday after discussions with his colleagues in the department.

According to a new RKI evaluation, the corona vaccinations in Germany are probably more recorded in the reporting statistics than before. It can be assumed that among the adults up to 84 Percent at least once and up to 80 percent are fully vaccinated , according to a current RKI report dated October 5th. That would correspond to five percentage points higher vaccination rates than according to official reports from the vaccination centers.

Holetschek now wants to know from the RKI how the data got into the system , where there were any deficits, whether it was due to a lack of data from company doctors, for example. That is why RKI President Lothar Wieler was invited for the next switch , to clear things up. “That will certainly be a lesson from the pandemic overall that we have not been very successful with the data bases so far from my point of view and there is an urgent need for improvement have “, added Holetschek. (dpa)

EU Commission approves aid for trade fair Failures in Germany

Organizers of trade fairs and exhibitions are allowed, according to a decision by the EU Commission due to the corona crisis , with up to 150 Millions of euros are supported . The Brussels authority approved a corresponding aid measure from Germany on Monday. The money is to be used to offset costs incurred in organizing events if these have been canceled due to corona measures.

Specifically, it is about events that occurred between October 1st 2021 and the 30. September 2022 were planned . “The measure is open to organizers of all sizes who are active in Germany ,” it said. Since no more than the actual loss is compensated and only damage that is related to hygiene restrictions is compensated, the Commission sees no risk that the We competition will be distorted.

The EU competition watchdogs already had a 642 – Million dollar rescue package approved for the German trade fair and congress industry . She has been particularly hard hit by the pandemic. (dpa)

Thailand opens borders for vaccinated air travelers from abroad from November 1st

Thailand opens its borders from November 1st to fully vaccinated air travelers from abroad. Tourists from ten countries that are considered to be low-risk countries will initially be admitted, as Prime Minister Prayut Chan-O-Cha explained on Monday. In addition to Germany, this includes the USA, China, Great Britain and Singapore . In December, the regulation is to be extended to other countries.

The condition is that the affected persons present a negative PCR test upon arrival and test themselves again after entry let said Prayut. “After that, they can travel as freely as Thai people”. Vaccinated tourists are currently quarantined in a hotel for at least seven days. An exception is the island of Phuket, where vacationers are allowed to move freely and can travel to other regions after a week.

Prayut admitted that the decision could lead to an increase in corona infections . But it is important to give the people in Thailand an economic perspective again . The corona pandemic has severely affected the tourism sector, which is important for the Thai economy. (AFP)

65, 3 percent fully vaccinated – around 1 million booster vaccinations

In Germany 60, 3 percent of the population fully vaccinated against the coronavirus . The rate among adults on Sunday was 75, 8 percent, according to data from the Robert Koch Institute (RKI) on Monday. Have been vaccinated against the virus at least once 68, 5 percent of all citizens, and 79, 3 percent of adults. Among the children and adolescents of 12 until 17 years have meanwhile 43, 2 percent get at least one first injection , 37, 0 percent are fully vaccinated.

The RKI assumes, however, that among adults probably more people are vaccinated than the data suggest. In a report at the beginning of October it was said that the quota for once and completely vaccinated persons had decreased 18 Years is likely to be up to 5 percentage points higher. A booster vaccination has already been given to over a million people in Germany . The RKI gave the value on Monday with 1. 20. 344 at. (dpa)

World Bank: poorer countries miss recovery from corona crisis

According to the World Bank, poorer countries hardly benefit from the economic recovery from the Corona crisis. The upswing is “dramatically unequal” , and developing countries are still facing major challenges, warned World Bank President David Malpass on Monday at the beginning of the organization’s annual meeting with the International Monetary Fund (IMF). Because the poorer countries lack vaccines and the financial leeway to support the economy, inequality between groups of countries is growing .

“The per capita income in industrialized countries should 2021 grow by almost 5 percent, but only 0.5 percent in the poor countries, ”said Malpass. For many developing countries, it will take years before income levels return to pre-pandemic levels. The pandemic led to a “tragic reversal” of the trend for developing countries and poverty reduction .

According to the World Bank the debt of poor countries increased 2020 around 12 Percent on 860 Billion dollars. The debt slows down the development of many poorer countries and must be brought to a sustainable level, said Malpass. “ We need a comprehensive approach to the debt problem , including debt reductions, faster restructuring and improved transparency.”

Finance ministers, central bankers and representatives from the financial sector and development cooperation come together for the annual meeting of the IMF and World Bank . The conference, which lasts until Sunday, takes place in a hybrid format, i.e. partly in Washington and partly online . The German Finance Minister Olaf Scholz , Bundesbank chief Jens Weidmann and the head of the European Central Bank, Christine Lagarde, also want to take part in some deliberations. (dpa)

US-Pharmakonzern Merck & Co.
US pharmaceutical company Merck & Co. Image: REUTERS / Brendan McDermid

Merck & Co. applies for emergency approval for corona drug in the USA

The US Pharmaceutical company Merck & Co. has applied for emergency approval for its corona drug Molnupiravir in the USA. In view of the “urgency” in the fight against the pandemic , his company had already ten days after receiving the data from the Phase 3 clinical trial has submitted a corresponding application to the FDA, Merck CEO Robert Davis said on Monday. He announced further applications in other countries .

The application is an important step on the way to a simple pill for the treatment of Covid – 19 . At the beginning of October, Merck and its partner Ridgeback Biotherapeutics announced that molnupiravir halved the risk of hospitalization or fatal disease in infected patients .

According to this, 7.3 percent of the 385 Patients with light or medium Covid – 18 – Symptoms receiving the antiviral drug hospitalized . There was no death. In the test group with 377 Patients who received a placebo were included in 14, 1 percent of cases resulted in hospital admission or fatal outcome. Specifically, eight patients died.

A number of pharmaceutical companies are currently working on antiviral drugs against Covid – 19. Such drugs are designed to prevent viruses from entering body cells or multiplying there. Molnupiravir is the first antiviral drug in pill form to receive approval . The antiviral drug Remdesivir is given intravenously. (AFP)

Malaysia reached adult – vaccination rate of 90 percent

Malaysia has reached an important milestone with its vaccination campaign: 90 Percent of the adult population in the Southeast Asian country are now vaccinated twice against the coronavirus. Because the number of infections continues to fall, a strict lockdown that was imposed in May was relaxed on Monday.

“We are on the descent from the peak of disaster and despair,” said Health Minister Khairy Jamaluddin on Twitter.

It is still unclear when tourists will be allowed to return to the popular holiday destination. The borders of Malaysia have been in place since March 2020 closed. In the state with 33 million inhabitants, more than 2.3 million infections have been confirmed so far. Around 27. 000 People are in connection with Covid – 19 died. (dpa)

Russia continues to post record deaths

In Russia, the number of people who die every day in connection with a coronavirus infection is still at a record level. On Monday, the government task force reported 957 additional deaths. That was only eleven fewer than two days ago, than with 968 Dead the highest value within 24 hours since the pandemic began.

According to the task force, 29. 409 New infections registered after 28. 647 On Sunday. Moscow is particularly hard hit with more than 5000 New infections.

Overall, Russia has the fifth most infections worldwide and the fourth most corona deaths. Around 7.8 million people have been shown to have contracted the virus, more than 217. 000 People died according to official information. (Reuters)

Ministry of Health defends end of free tests

The Federal Ministry of Health defended the expiry of the free citizen tests for most people at the beginning of the week. Everyone had the opportunity to protect themselves and get vaccinated. One could no longer expect citizen tests to be offered at the expense of the general public , said a spokeswoman. Health Minister Jens Spahn had previously spoken of “fairness in front of the taxpayer”. (dpa)

Eine Studie bestätigt die Wirksamkeit von Corona-Impfungen.
A study confirms the effectiveness of corona vaccinations. Image: dpa / Sebastian Gollnow

Study: lower corona vaccinations Risk of severe disease progression by 34 Percent

Corona- According to a new French study, vaccinations protect very effectively against severe Covid – 17 – also in the case of the highly contagious Delta variant. “People who have been vaccinated have nine times less risk of being hospitalized or of Covid – 19 to die as unvaccinated “, explained the epidemiologist Mahmoud Zureik, head of the scientific group Epi-Phare, which published the results of their study on Monday Scientists the data from 22 Millions of people over 50 years in the period from 27. December 2020 until 20. July. It was found that vaccinated people had a 65 percent had a lower risk of hospitalization or fatal disease than those who had not been vaccinated. The effect of the vaccines from Biontech / Pfizer, Moderna and Astrazeneca was examined.

The latest study confirms similar findings the USA, Great Britain and Israel. According to the French scientists, however, it is the largest study of its kind to date. It also suggests that the protection against severe courses in the study period of five months is not

For their study, the researchers compared the data of eleven million people who were vaccinated with those of eleven million people who were not vaccinated. They also took into account gender, age and the region in which the affected persons lived. (AFP)

Epi-Phare demonstrated a similarly high protective effect for the Delta variant: It was not suitable for humans 75 years at 84 percent, for people between 50 and 75 years at 92 percent. In the case of the delta variant, however, the scientists came out in favor of follow-up studies, since the data situation only referred to one month. The highly contagious virus variant had only appeared in France in June.

Bund und Länder diskutieren über Testpflicht
Federal and state governments discuss compulsory testing Image: dpa / Daniel Reinhardt

Federal and state governments advise on compulsory tests at certain workplaces

The federal government and the federal states are currently discussing uniform regulations for employees in companies with public traffic Companies, institutions or other offers with direct customer contact not only for customers en, visitors or other external persons, but should also apply to employees ”, it says in a draft resolution that the health ministers want to vote on at their conference on Monday afternoon the “Business Insider” reported that the dpa is also available. According to information from the German Press Agency, there is still no uniform line on voting behavior among the federal states, which is why changes are still possible.

With a ” In principle, uniform procedure “throughout Germany, a discrepancy in the test regulations for employees in professional activities with direct customer contact should be avoided as far as possible, the draft also says. For this purpose, all countries that have not yet issued any regulations in this regard should implement them promptly in their Corona regulations.

Accordingly, all people who are not vaccinated or who have no evidence of recovery would have to undergo a test when they go to work. The test requirement can also be linked to other parameters such as incidences the paper says. And: “The frequency of test evidence and the possibility of equivalent alternative measures can be decided individually for each area.” (Dpa)

Corona tests are now also chargeable in Switzerland

Since Monday, corona tests are no longer free for many people in Switzerland. The costs for a test vary greatly depending on the provider. Antigen tests can be 30 to over 50 Francs (more than 46 Euro) costs, PCR tests around 150 Francs. The tests are still available for free under 16 – year olds, for First vaccinated persons and people suspected of having a coronavirus infection or those who cannot be vaccinated for medical reasons. Programs with regular tests in schools and companies also remain free.

Since mid-September, a Corona certificate has to be shown in the interior of restaurants, cultural and leisure facilities as well as at events inside. It proves that the person has been vaccinated, recovered or tested (3G rule). German certificates are recognized in Switzerland.

Since only barely 055 percent of all people in Switzerland have been fully vaccinated to date , the government has started a new vaccination initiative . This includes 50 Further mobile units that offer vaccination without registration where there are many people. The Minister of Health has proposed that people who convince others to vaccinate should be given a voucher for 50 Francs (47 Euro). Most cantons reject this as a false incentive or because of the risk of abuse. (dpa)

Schools and universities in Pakistan back to normal operation

After more than one and a half years of pandemic-related interruptions Tens of thousands of educational institutions in Pakistan resumed normal operations on Monday. The South Asian country with more than 220 million inhabitants in February 2020 ordered schools and universities to close when the first coronavirus infections were reported. Finally, the classes were allowed to start with 50 percent are occupied.

The decision to allow “normal” lessons was made due to the lower spread of the coronavirus and the start of the school vaccination program, explained the pandemic fight responsible minister Asad Umar on Twitter. Most recently, the number of new infections with the coronavirus in the country had fallen sharply.

So far, more than 1.2 million infections and more than 28 000 Officially proven deaths related to the virus. It is assumed that the actual numbers are significantly higher.

Authorities have now also vaccinated children from 12 years allowed and started. Strong restrictions have been put in place for people without vaccination. You are no longer allowed to take the train, use domestic flights, or go to shopping centers or restaurants. So far, according to the Ministry of Health, more than 89 Millions of people receive at least one dose of vaccine. This means that Islamabad is below the target by the end of the year 80 To have fully vaccinated millions of citizens. (dpa)

Visiting nightclubs and major events in Wales only with vaccination certificate

In Wales, visitors to nightclubs and major events have been required to present a vaccination certificate or proof of a negative corona test since Monday. The UK’s education minister Jeremy Miles told the BBC on Monday that the ruling would help contain the spread of the virus and ease the burden on health services in the upcoming winter. The evidence is mandatory for 18 – year olds.

In the United Kingdom, all parts of the country are responsible for their own health policy. With the measure, the government of Wales goes further than the central government in London, which is responsible for most of England. There a majority in the ruling Conservative Party has so far rejected the introduction of vaccination certificates.

Parliament in Cardiff voted in favor of the introduction last Tuesday by a wafer-thin majority . The pass must be presented for discos and night clubs, for events in closed rooms with at least 500 and outdoors with at least 4000 participants as well basically for events with at least 10 000 People. The government wants to criminalize falsifying negative tests. (dpa)

Holetschek: “Vaccination is the Get out of the pandemic, don’t test “

Bayerns Gesundheitsminister Klaus Holetschek
Bavaria’s Minister of Health Klaus Holetschek Picture: dpa

Bavaria’s Minister of Health Klaus Holetschek (CSU) has defended the end of the free corona tests. “Vaccination is the way out of the pandemic, not testing,” he told Bayerischer Rundfunk (BR 24). “We now have the possibility of vaccination, then I think it is consistent to say on the other side, that we are reducing the free of charge for certain tests and no longer billing them at the expense of the solidarity community.

With a view to autumn and winter, Holetschek emphasized that The pandemic is not over yet. He appealed to all unvaccinated people to get vaccinated in order to “make a contribution for themselves, but also for society as a whole” . (dpa)

Survey: Corona stresses students and trainees heavily

Two fifths of all students and apprentices feel very stressed by the corona pandemic and the associated restrictions. This is shown by a Forsa survey on behalf of the KKH commercial health insurance company. Nearly 40 Percent of respondents in both groups reported depressive symptoms during the viral crisis and said they were irritated more quickly than usual and to be more often demotivated.

“Around a quarter of college students and apprentices also report physical complaints such as headaches, stomach pains and tension as well as problems falling asleep or staying asleep” , so the KKH. With a view to their own education fear 65 Percentage of those surveyed that important internships and semesters abroad are difficult to plan in the coming months .

Almost half are also worried about having to catch up on learning material, like that that there will be a delay in training or studies. The vast majority (73 percent), with a view to the coming months, is mainly concerned with renewed contact restrictions , which also brings the fear of loneliness (44 Percent). Almost half of the students and trainees rely on their own strategies to cope with high psychological stress. (dpa)

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